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Postbiotic supplements from US brands and US-based sellers

7 US brands and sellers surfaced here at $28.00 to $59.99, each verified from Amazon's own published seller info. Last verified October 17, 2026.

Amazon ranks by what sells fastest, so a postbiotic supplement from an established brand gets buried under cheap imports no matter how far you scroll. This page lists the US brands and US-based sellers for postbiotic supplements, so you can start from the ones worth trusting.

We read each seller's registered country from Amazon's own published seller info. We don't claim anything here is manufactured in the US, only that you're buying from a US brand or a US-based seller.

Quick comparison

Confirmed US brands and sellers for postbiotic supplements: brand, price, and seller location
BrandPriceSeller
Ancient Nutrition$46.71US brand
BIOptimizers$28.00US brand
Just Thrive$49.99US brand
Pendulum$59.99US brand
Physician's Choice$39.99US brand
Seed$34.99US brand
Hyperbiotics$29.98US-based seller

Confirmed US brands and sellers

7 listings where Amazon's own seller info places the seller in the US. Each badge says which.

Ancient Nutrition SBO Probiotic Trinity Daily Care, Probiotics for Digestive Health, 40 Billion Blend of Prebiotics, Probiotics, Postbiotics, and Parabiotics Reduces Occasional Bloating, 60 Count
Ancient Nutrition🇺🇸 US brand

Ancient Nutrition SBO Probiotic Trinity Daily Care, Probiotics for Digestive Health, 40 Billion Blend of Prebiotics, Probiotics, Postbiotics, and Parabiotics Reduces Occasional Bloating, 60 Count

$46.71
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BIOptimizers Cognibiotics, Brain Supplement, Mood & Focus, 30 Capsules | Probiotic Brain Supplement for Mood, Focus, Memory & Mental Clarity
BIOptimizers🇺🇸 US brand

BIOptimizers Cognibiotics, Brain Supplement, Mood & Focus, 30 Capsules | Probiotic Brain Supplement for Mood, Focus, Memory & Mental Clarity

$28.00
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Just Thrive Probiotic & Antioxidant 100% Spore-Based Digestive Support | 30 capsules, 100% spore-based probiotic and antioxidant formula, Gluten free, Supports digestive and immune health
Just Thrive🇺🇸 US brand

Just Thrive Probiotic & Antioxidant 100% Spore-Based Digestive Support | 30 capsules, 100% spore-based probiotic and antioxidant formula, Gluten free, Supports digestive and immune health

$49.99
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Pendulum Metabolic Daily - Multi-Strain Probiotic with Akkermansia muciniphila to Support Metabolism and Sustain Energy Levels - for Women and Men - 30 Capsules (1 Pack)
Pendulum🇺🇸 US brand

Pendulum Metabolic Daily - Multi-Strain Probiotic with Akkermansia muciniphila to Support Metabolism and Sustain Energy Levels - for Women and Men - 30 Capsules (1 Pack)

$59.99
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Physician's CHOICE 60 Billion Probiotic Advanced 3-in-1 + Postbiotic - 30ct | Advanced Formula - 12 Strains + Postbiotic & Organic Prebiotics for Bloating, Mood, Sleep, Immune, Digestive & Gut Health
Physician's Choice🇺🇸 US brand

Physician's CHOICE 60 Billion Probiotic Advanced 3-in-1 + Postbiotic - 30ct | Advanced Formula - 12 Strains + Postbiotic & Organic Prebiotics for Bloating, Mood, Sleep, Immune, Digestive & Gut Health

$39.99
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Seed PM-02 Sleep + Restore - for Adults - 30-Day Supply with Jar | Non-Habit Forming - Gentle Low-Dose Melatonin & Ashwagandha - Supports Natural Sleep Rhythms°
Seed🇺🇸 US brand

Seed PM-02 Sleep + Restore - for Adults - 30-Day Supply with Jar | Non-Habit Forming - Gentle Low-Dose Melatonin & Ashwagandha - Supports Natural Sleep Rhythms°

$34.99
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Vital Nutrients Leaky Gut Defense Probiotic, 60 Tablets | Hyperbiotics Probiotics, Strengthens Intestinal Barrier and Gut Health,* Supports Digestive Comfort, Vegan
Hyperbiotics🇺🇸 US seller

Vital Nutrients Leaky Gut Defense Probiotic, 60 Tablets | Hyperbiotics Probiotics, Strengthens Intestinal Barrier and Gut Health,* Supports Digestive Comfort, Vegan

$29.98
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US brands we went looking for

More names an AI suggested for this category that we haven't confirmed US on yet. Each badge says how far we've checked it.

Suggested, not verified. These names came from an AI suggestion, not from our data. We only call a brand US after checking the seller's registered address on its Amazon seller page. Amazon is the seller on these, so its seller page can't tell us who the brand is.

New US finds, once a month

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